Edvard Munch, "The Scream", was done around 1893–1910.  He was born on a farm in Loten, Norway, in 1863, and was the second of five children of Christian Munch, a doctor in the Army Medical Corps, and his wife Laura. The family moved to Oslo, then known as Christiania, a year later and had not been there long when the first disaster struck. Munch was just five years old when his mother died of tuberculosis. His aunt moved in to the family home to take care of the young children. Nine years later his elder sister Sophie succumbed to the same illness.  "The Scream",  by Edvard Munch is a disturbing icon of modern art that we all can identify with. We know what it is to feel as the subject does and his plight generates fear and sympathy in equal measure.  The painting screams the mood of severe anxiety that Munch was feeling and experienced at the time he painted this piece of work.  I can relate to this painting because I myself have experienced some sort of anxiety in this life.  He was a very disturbed artist who was a part of the expressionism era.
"My friends walked on and there I still stood, trembling with fear - and I sensed a great, infinite scream run through nature."
- Edvard Munch

reference:  http://www.smithsonianmag.com/arts-culture/munch.html